Efficacy of Multiple Low-dose Photodynamic Therapy in Nude Mice Implanted with Cervical Cancer

In recent years, although the widespread screening of cervical cancer, especially the systemic use of the Papanicolaou (Pap) smear (Cronje, 2005), cervical cancer remains the second most common cause of death from cancer in women worldwide (Sreejata et al., 2012), China accounts for 29% of the 51,000,000 new cases of cervical cancer each year (Kim et al., 2009). But due to cervical cancer screening, cervical cancer can be detected early and is younger trend, expecially early cervical cancer and cervical intraepithelial neoplasia (CIN), some young patients with no children had a strong desire for fertility. So in addition to traditional treatments including operation, chemotherapy and radiotherapy, photodynamic therapy may become an alternative treatment. Photodynamic therapy (PDT) is an emerging tumor treatment approach in recent years. Since 20 years ago, Clinical study of Dougherty on photodynamic therapy of treating malignant tumor was successful for the first time (Thomas et al., 1978), which caused a lot of clinical